Pharmaceutical Injection Manufacturer In Panchkula by Adept Biocare.
Alpha Beta Arther is synthetised from Artemisinin using methanol and a catalyst in hydrochloric acid medium. This
results in the production of predominantly βα-artemether. The alpha-epimer is also present and causes a difficult purification of the product.Both the alpha and the βα-epimers are active antimalarials.
It is the purification and separation of alpha from βαthat leads to low yields and hence this increases the cost
price of Artemether significantly.
Artemether has major antimalarial properties. Chloroq-uine-resistant or multi-resistant strains of P.falciparum have a great susceptibility to Artemether. The schizont-icidal activity of Artemther is due to the destruction of the asexual erythrocytic forms of P.falciparum and P.
vivax. Artemether is effective against all strains resistant to the other antimalarial agents. No cross-resistance is detected with chloroquine.